高压氧
颌骨骨坏死
医学
清创术(牙科)
阶段(地层学)
外科清创术
外科
介绍(产科)
高压氧
病理
古生物学
骨质疏松症
双膦酸盐
生物
作者
Lawrence J Lin,Alison R Alfonso,Frank L Ross,Ernest S Chiu,Kenneth E. Fleisher
出处
期刊:Undersea & Hyperbaric Medicine
[Undersea and Hyperbaric Medical Society (UHMS)]
日期:2020-01-01
卷期号:: 241-251
被引量:1
标识
DOI:10.22462/04.06.2020.10
摘要
The definition of medication-related osteonecrosis of the jaw (MRONJ) includes a stage 0 presentation where exposed bone, the hallmark of this condition, is absent. Numerous management strategies have been recommended for MRONJ including hyperbaric oxygen (HBO2) therapy. This report describes a 64-year-old woman with stage 0 MRONJ of the bilateral mandible, refractory to clindamycin and local debridement, who was subsequently managed successfully with amoxicillin/clavulanate and HBO2 therapy. The authors also explore the current literature on the pathophysiology of MRONJ and the potential role of hyperbaric oxygen in its treatment.
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