Disulfide Promoted C−P Bond Cleavage of Phosphoramide: “P” Surrogates to Synthesize Phosphonates and Phosphinates

Abstract A metal‐free C−P bond cleavage reaction is described herein. Phosphoramides, a phosphine source, can react with alcohols to produce phosphonate and phosphinate derivatives in the presence of a disulfide. P−H 2 , P‐alkyl, and P,P‐dialkyl phosphoramides can be used as substrates to obtain the corresponding pentavalent phosphine products. magnified image