医学
内科学
心脏病学
脑梗塞
冲程(发动机)
梗塞
脑梗塞
作者
Steven G. Pavlakis,E. Steve Roach
出处
期刊:Neurology
[Ovid Technologies (Wolters Kluwer)]
日期:2018-01-16
卷期号:90 (3): 105-106
标识
DOI:10.1212/wnl.0000000000004839
摘要
The occurrence of large cerebral infarctions due to sickle cell disease (SCD) has been known for many years, but it was not until 1988 that brain MRI documented 7 lesions consistent with subclinical infarction in 6 children with SCD who had experienced no prior signs or symptoms of stroke.1 Five of these 6 children had T2 hyperintensity abnormalities located in border zone regions. Such lesions were eventually characterized as a silent cerebral infarction (SCI). The presence of SCIs predicts both future SCIs and overt stroke.2
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