Prognostic value of cytokines in acute panvcreatitis

Several studies tried to define the proinflamatory and anti-inflamatory cytokine response in acute pancreatitis. In our prospective studywe focused on the role of IL-6, IL-8, and IL-10 in the prognosis of acute pancreatitis. One hundred and seventeen consecutive patients(65 males and 52 females) with diagnosis of acute pancreatitis were eligible for participation in the study. Conclusions: Pts with severe acute pancreatitis had elevated values of IL-6, IL-8 and IL-10. Because of its sensitivity, elevated IL-6 should be considered in the prediction of acute pancreatitis complications.