材料科学
癌症免疫疗法
共价键
免疫疗法
吸收(声学)
光动力疗法
免疫检查点
封锁
癌症
纳米技术
癌症研究
癌症治疗
医学
化学
生物化学
内科学
有机化学
受体
复合材料
作者
Leilei Yang,Liang Zhang,Shu-Yen Wan,Shuo Wang,Zhi‐Zhong Wu,Qi‐Chao Yang,Yao Xiao,Hexiang Deng,Zhi‐Jun Sun
标识
DOI:10.1002/adfm.202170315
摘要
Cancer Immunotherapy In article number 2103056, Hexiang Deng, Zhi-Jun Sun, and co-workers utilize a covalent organic framework with excellent two-photon absorption (2PA) property as a novel approach to generate photosensitizers for efficient cancer immunotherapy. This is attributed to their high ROS generation capability, which could further induce robust immunogenic cell death and boost antitumor immunity. This work describes a new approach for synergizing photodynamic therapy with immune checkpoint blockade therapy by using 2PA covalent organic frameworks.
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