Application of SF-Cube 2.0 Technology in Platelet Count in Patients with EDTA-Dependent Pseudothrombocytopenia

Background To explore the application of SF-Cube 2.0 technology in platelet in patients with EDTA-dependent pseudothrombocytopenia (EDTA-PTCP). Methods Twenty-two out-patients and in-patients with EDTA-PTCP in our hospital were selected from February 1, 2020, to August 31, 2020. With the permission of each patient, blood samples of EDTA and sodium citrate anticoagulant tubes were collected. EDTA anticoagulant samples were tested by using the complete blood cell and white blood cell differential count(CD) mode, and complete blood cell count, white blood cell differential count, and reticulocyte count (CDR) mode of the Mindray BC-6800Plus automated hematology analyzer, and the platelet counts were compared with the sample of sodium citrate anticoagulant from this patient. Results As SF-Cube 2.0 technology (implemented by using the CDR mode of the Mindray BC-6800Plus) was used, the platelet of EDTA-PTCP sample was consistent with that of sodium citrate anticoagulant, which was significantly higher than that of CD detection mode. Conclusions SF-Cube 2.0 technology can effectively correct the platelet counts in people with known or suspected EDTA-PTCP.