Selective Pd(0)-Catalyzed Arylations with New Electrophilic or Nucleophilic Multi-Coupling Reagents

All articles of this category Reaction conditions have been developed allowing the selective coupling of arylzinc reagents with aryl iodides at rt (Pd(dba) 2 cat, tfp cat) and aryl triflates at 65 °C, (Pd(dba) 2 cat, dppf cat). Thus, o, m, p -iodoaryl triflates could be used as efficient multi-coupling reagents and selectively reacted with two different organozincs leading to various terphenyls. A new synthesis of diarylzincs starting from an arylsilane has also been found. After a successive silicon-boron and boron-zinc exchange, the diarylzinc is obtained in good yield and used as a nucleophilic multi-coupling reagent. palladium-catalyzed cross-coupling - polyfunctional biphenyls and terphenyls