医学
补体系统
发病机制
免疫学
血管闭塞
免疫系统
补语(音乐)
呼吸窘迫
病理
内科学
生物化学
化学
麻醉
互补
基因
表型
作者
Steven B. Abramson,Belmont Hm,Patricia Hopkins,Buyon Jp,Robert Winchester,Gerald Weissmann
出处
期刊:PubMed
日期:1987-06-01
卷期号:14 Suppl 13: 43-6
被引量:11
摘要
The deposition of immune complexes within blood vessel walls results in the potential for complement activation and the release of chemotactic factors, such as fragments of C5 (C5fr). The generation of C5fr results in the intravascular aggregation of neutrophils with subsequent leukostatic occlusion of the pulmonary arterioles. The generation of C5fr may contribute to the pathogenesis of adult respiratory distress syndrome and other diseases. Studies were undertaken to determine the role of circulating complement derived peptides and intravascular neutrophil activation in systemic lupus erythematosus.
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