Efficacy of radiotherapy and chemotherapy in treatment of small cell lung cancer confirmed after operation-Analysis of treatment in 44 patients

Objective To analyze and evaluate retrospectively the efficacy of chemotherapy and radiotherapy in 44 patients with small cell lung cancer(SCLC) confirmed after operation.Methods Fortyfour patients with SCLC:stage Ⅰ,15 cases(34.1%),stage Ⅱ,13 cases(29.6%),stage Ⅲ,12 cases(27.3%) and stageⅣ,4 cases(9.1%) were analyzed.All of them had undergone radical operation except 1 segmentectomy case,and all received chemotherapy for 4-8 cycles withetoposide + cisplatin or carboplatinortaxinol + cisplatin or carboplatinregimen after operation.The patients were followed up for 1,3,5year survival rates.Results The 1,3,5-year survival rates of 44 cases were 84.3%,48.2% and 18.1% respectively.The efficacy of the postoperative treatment with combined chemotherapy and radiotherapy for stageⅠandⅡcases was good,but was not useful for stage Ⅲ and Ⅳ cases.Conclusion Postoperative treatment with combined chemotherapy and radiotherapy had good therapeutic effects for stagesⅠandⅡ SCLC.