Efficacy and Safety of Muscarinic Antagonists Combined with Adrenergic alpha-Antagonists in the Medical Expulsion Therapy for Distal Ureteral Stone: A Meta-Analysis

Combination therapy with alpha-blockers and muscarinic antagonists improves stone expulsion and symptomatic relief in patients with lower ureteral stones <10 mm, without significantly affecting stone passage time, but at the cost of more anticholinergic side effects.