化学
吡唑
环加成
产量(工程)
1,3-偶极环加成
组合化学
有机化学
立体化学
催化作用
冶金
材料科学
作者
Yulin Wang,Cheng Xiong,Jiacheng Zhong,Qingfa Zhou
出处
期刊:Tetrahedron
[Elsevier]
日期:2022-06-01
卷期号:115: 132790-132790
被引量:5
标识
DOI:10.1016/j.tet.2022.132790
摘要
A strategy for the 1,3-dipolar cycloaddition of nitrilimines to δ-allenoates has been developed to provide various 1,3,5-trisubstituted pyrazole-4-carboxylates and pyrazole-4 -carboxamide derivatives, which have excellent anticancer effects. This protocol exhibits characteristics of good yield, mild reaction condition, facile operation process and post-processing steps.
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