A Review on Chemical and Biological Studies of 4-Chromanone Derivatives

The chroman-4-one skeleton is a remarkable structural system that belongs to oxygen-containing heterocycles. It constitutes a major building block in a large class of medicinal compounds, and synthetic chroman-4-one derivatives exhibit a broad spectrum of significant biological and pharmaceutical activities. This review article highlights the synthesis and reactions of 4-chromanone derivatives possessing important pharmaceutical activities.