免疫系统
平衡
生物
获得性免疫系统
细胞生物学
免疫学
干扰素
先天免疫系统
抗原
作者
Fabrizio Mattei,Giovanna Schiavoni,David F. Tough
标识
DOI:10.1016/j.cytogfr.2010.05.002
摘要
Although initially identified and best characterized for their role in innate antiviral defence, type I interferons (IFN-I) are also known to have an important impact on the adaptive immune response. In part, this is linked to another long-recognised property of IFN-I, namely their ability to modify cellular proliferation and survival. Here, we review the influence of IFN-I on immune cell homeostasis, focusing on their effects on T cells and antigen-presenting cells.
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