Multivariate analysis of prognostic factors in 267 cases of endometrial carcinoma

Objective To investigate the survival analysis of endometrialcarcinoma, and to explore its prognostic factors.Methods A total of 267 patients with endometrial carcinoma in our hospital from Jan. 2000 to Jan. 2004 were studied retrospectively. Prognostic factors were analyzed by univariate and multivariate analysis.Results The total 3-year and 5-year survival rate of 267 cases were 90.8% and 88.1%. The univariate analysis showed that operative stage, pathological type, histological grade, depth of muscularis invasion, lymph-node metastasis, adnexae metastasis, postoperation treatment, the expression of ER and PR significantly associated with the prognosis(P0.05). However, on multivariate analysis, only operative stage, pathological type, histological grade and the expression of PR significantly correlated with 5-year overall survival(P0.05).Conclusions The 5-year survival rate of endometrial carcinoma is comparatively high. Operative stage, pathological type, histological grade and the expression of PR are independent prognostic factors of endometrial carcinoma.