Introduction of the Acyl Group at the C7 Position of Indole via N ‐Acyl Indole Photo‐Fries Rearrangement Under UV ‐C

ABSTRACT This study focused on the selective introduction of an acyl group at the C7 position of indole via amide photo‐Fries rearrangement. Utilizing UV‐C as the sole light source, the N ‐acyl group of indoles was successfully rearranged across the bridging carbon to the α‐position. This approach enabled a mild reaction and environmentally friendly conditions. The acyl substituent must be small or aliphatic to undergo successful rearrangement, unlike acyl radicals with larger or aromatic substituents.