癌症研究
基因沉默
膀胱癌
恶性肿瘤
转移
小RNA
细胞生长
体内
细胞培养
癌症
基因敲除
生物标志物
细胞周期
化学
生物
医学
病理
内科学
基因
生物化学
遗传学
生物技术
作者
Jiahe Yi,Xueyou Ma,Yufan Ying,Zixiang Liu,Yijie Tang,Xuan Shu,Jiazhu Sun,Yuqing Wu,Dingheng Lu,Xiao Wang,Jindan Luo,Ben Liu,Xiangyi Zheng,Yiwei Lin,Jiangfeng Li,Liping Xie
出处
期刊:Cancer Letters
[Elsevier BV]
日期:2024-01-09
卷期号:585: 216613-216613
被引量:12
标识
DOI:10.1016/j.canlet.2024.216613
摘要
Several studies have indicated that circular RNAs (circRNAs) play vital roles in the progression of various diseases, including bladder cancer (BCa). However, the underlying mechanisms by which circRNAs drive BCa malignancy remain unclear. In this study, we identified a novel circRNA, circPSMA7 (circbaseID:has_circ_0003456), showing increased expression in BCa cell lines and tissues, by integrating the reported information with circRNA-seq and qRT-PCR. We revealed that circPSMA7 is associated with a higher tumor grade and stage in BCa. M
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