乙二醇中毒
乙二醇
医学
重症监护医学
化学
有机化学
作者
Kehu Yang,Hogahemat Xiao Kelaiti,Peng Peng
出处
期刊:PubMed
[National Institutes of Health]
日期:2024-10-20
卷期号:42 (10): 788-793
标识
DOI:10.3760/cma.j.cn121094-20231106-00101
摘要
Acute ethylene glycol poisoning often leads to acute kidney injury, and delays in diagnosis and treatment can lead to severe multi-organ dysfunction and even death. At present, there is a lack of specific laboratory tests that can be used for rapid clinical diagnosis, and diagnosis and evaluation only rely on medical history, clinical symptoms, and non-specific laboratory test results. Key treatments include alcohol dehydrogenase inhibitors (fomcpizole or ethanol) and hemodialysis, which is not approved in China. A clear understanding of the mechanism of toxicity, pathophysiology, clinical manifestations, efficacy and limitations of laboratory tests, and treatment options after ethylene glycol poisoning can help accelerate the early diagnosis, treatment, and prognosis of patients after ethylene glycol poisoning. This article reviews this article in order to provide a reference for clinicians.
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