Notice to Subscribers With this issue, Peter M. Staats, MD, takes over as the editor of Topics in Pain Management, replacing Joel R. Saper, MD. Dr. Saper helped make this publication a top-drawer newsletter in the field of pain management, and we thank him for his enormous contribution to its success. Dr. Staats is Associate Professor in the Department of Anesthesiology and Critical Care Medicine and the Department of Oncology at The Johns Hopkins University School of Medicine in Baltimore, Maryland, and is one of the leading authorities in the world today in pain management.—Daniel E. Schwartz, Publisher