试剂
胺气处理
对映体
聚合物
分辨率(逻辑)
动力学分辨率
组合化学
化学
选择性
有机化学
计算机科学
对映选择合成
催化作用
程序设计语言
作者
Imants Kreituss,Yuta Murakami,Michael Binanzer,Jeffrey W. Bode
标识
DOI:10.1002/anie.201204991
摘要
Shake it up baby! Simply shaking a polymer-supported reagent and the racemic amine at room temperature kinetically resolves a broad range of N-heterocycles with good selectivity. The polymer-supported reagents are robust, easy to regenerate, and can be reused dozens of times. Cleavable acyl groups can be used to give access to both amine enantiomers in a single resolution. Detailed facts of importance to specialist readers are published as ”Supporting Information”. Such documents are peer-reviewed, but not copy-edited or typeset. They are made available as submitted by the authors. Please note: The publisher is not responsible for the content or functionality of any supporting information supplied by the authors. Any queries (other than missing content) should be directed to the corresponding author for the article.
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