The organocatalytic enantiodivergent fluorination of β-ketodiaryl-phosphine oxides for the construction of carbon-fluorine quaternary stereocenters

We developed, for the first time, the cinchona-alkaloid-catalyzed enantiodivergent α-fluorination of β-keto diarylphosphine oxides, which resulted in two enantiomers bearing fluorine-containing quaternary stereocenters.