Objective:To study the relationship between acute pancreatitis and serum triglyceride contents.Methods:The levels of serum triglyceride and clinical data in 447 patients with acute pancreatitis admitted in our hospital from 2002~2007 were retrospectively analyzed.Results:Hypertriglyceridemia was observed in 24.2% patients.The incidence of hypertriglyceride-mia in severe acute pancreatitis was higher than that of mild acute pancreatitis.However,no significantly difference of the levels of triglyceride was found in that's two groups.The APACHE-II scores,computer tomography severity index(CTSI) and length of hospitalization in groups with higher triglyceride(TG≥11.3 mmol/L)were higher than that of groups with lower triglyceride(TG11.3 mmol/L)and normal groups.Conclusion:Patients with acute pancreatitis often have hypertriglyceridemia.Hyperlipidemia may aggravate the diseases and antilipemic procedures should be given as earlier as possible.