材料科学
生物相容性
组织工程
生物医学工程
傅里叶变换红外光谱
脚手架
热重分析
生物材料
骨组织
扫描电子显微镜
体内
化学工程
纳米技术
复合材料
冶金
生物技术
工程类
生物
医学
作者
Xing Li,Yayun Zhao,Bing Yue,Yaping Li,Ning Gan,Zhiyong Guo,Zhaoxiang Peng,Yabin Zhu
摘要
The macroporous materials were prepared from the transformation of cuttlebone as biotemplates under hydrothermal reactions and characterized by Fourier transform infrared spectroscopy (FTIR), X-ray diffraction (XRD), thermogravimetric/differential thermal analyses (TG-DTA), and scanning electron microscopy (SEM). Cell experimental results showed that the prepared materials as bone tissue engineering scaffolds or fillers had fine biocompatibility suitable for adhesion and proliferation of the hMSCs (human marrow mesenchymal stem cells). Histological analyses were carried out by implanting the scaffolds into a rabbit femur, where the bioresorption, degradation, and biological activity of the scaffolds were observed in the animal body. The prepared scaffolds kept the original three-dimensional frameworks with the ordered porous structures, which made for blood circulation, nutrition supply, and the cells implantation. The biotemplated syntheses could provide a new effective approach to prepare the bone tissue engineering scaffold materials.
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