Recently,crack of box girder and mid-span deflection are the main diseases in the operation of the long-span prestressed concrete(PC) continuous rigid frame box-girder bridges,and hasn’ t been effectively solved until to now.The structural finite analysis model of space was built relies on established engineering to study and analysis the influence of long-span PC continuous rigid frame bridge on working performance and stress situation caused by longitudinal and vertical prestressing loss、structure overweight、load time、deflection and so on.so we avoid the excessive cracking and deflection caused by the above factors,and provide the basis to improve this kind of bridge design and construction methods.