流产
医学
体外受精
胚胎移植
抗苗勒氏激素
妇科
逻辑回归
产科
怀孕
卵巢储备
混淆
不育
激素
内分泌学
内科学
生物
遗传学
作者
B. Tarasconi,Teddy Tadros,Jean Marc Ayoubi,S. Belloc,Dominique de Ziegler,Rénato Fanchin
标识
DOI:10.1016/j.fertnstert.2017.07.001
摘要
ObjectiveTo investigate whether serum antimüllerian hormone (AMH) levels are independently related to miscarriage rates after in vitro fertilization–embryo transfer (IVF-ET).DesignCohort study.SettingUniversity-affiliated IVF-ET center.Patient(s)A total of 1,060 patients who attained a clinical pregnancy after IVF-ET.Interventions(s)Centralized serum AMH measurements were performed within the 12 months before IVF-ET. Binary logistic regression was used to verify whether serum AMH levels were associated with the occurrence of a miscarriage independently from confounding factors, such as age and intensity of ovarian response to controlled ovarian stimulation assessed by the number of oocytes retrieved.Main Outcome Measure(s)Miscarriage rates.Result(s)In patients displaying reduced serum AMH levels, miscarriage rates were significantly increased independently from age and the number of oocytes retrieved.Conclusion(s)The present data indicate that serum AMH levels are independently associated with the occurrence of a miscarriage after IVF-ET. To investigate whether serum antimüllerian hormone (AMH) levels are independently related to miscarriage rates after in vitro fertilization–embryo transfer (IVF-ET). Cohort study. University-affiliated IVF-ET center. A total of 1,060 patients who attained a clinical pregnancy after IVF-ET. Centralized serum AMH measurements were performed within the 12 months before IVF-ET. Binary logistic regression was used to verify whether serum AMH levels were associated with the occurrence of a miscarriage independently from confounding factors, such as age and intensity of ovarian response to controlled ovarian stimulation assessed by the number of oocytes retrieved. Miscarriage rates. In patients displaying reduced serum AMH levels, miscarriage rates were significantly increased independently from age and the number of oocytes retrieved. The present data indicate that serum AMH levels are independently associated with the occurrence of a miscarriage after IVF-ET.
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