医学
安慰剂
射血分数
心力衰竭
心脏病学
内科学
肥厚性心肌病
利钠肽
脑利钠肽
心肌病
心室流出道
病理
替代医学
作者
Martin S. Maron,Ahmad Masri,Lubna Choudhury,Iacopo Olivotto,Sara Saberi,Andrew Wang,Pablo García‐Pavía,Neal K. Lakdawala,Sherif F. Nagueh,Florian Rader,Albree Tower‐Rader,Aslan T. Turer,Caroline Coats,Michael A. Fifer,Anjali Owens,Scott D. Solomon,Hugh Watkins,Roberto Barriales‐Villa,Christopher M. Kramer,Timothy C. Wong
标识
DOI：10.1016/j.jacc.2022.10.020
摘要
Aficamten resulted in substantial reductions in LVOT gradients with most patients experiencing improvement in biomarkers and symptoms. These results highlight the potential of sarcomere-targeted therapy for treatment of oHCM.
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