Issues With the Design of Randomized Trials of Temporary Mechanical Circulatory Support for Cardiogenic Shock

HomeCirculationVol. 147, No. 20Issues With the Design of Randomized Trials of Temporary Mechanical Circulatory Support for Cardiogenic Shock No AccessArticle CommentaryRequest AccessFull TextAboutView Full TextView PDFView EPUBSections ToolsAdd to favoritesDownload citationsTrack citationsPermissions ShareShare onFacebookTwitterLinked InMendeleyReddit Jump toNo AccessArticle CommentaryRequest AccessFull TextIssues With the Design of Randomized Trials of Temporary Mechanical Circulatory Support for Cardiogenic Shock Jonathan R. Dalzell Jonathan R. DalzellJonathan R. Dalzell Correspondence to: Jonathan R. Dalzell, MBChB, MD, Department of Transplantation and Mechanical Circulatory Support, Scottish National Advanced Heart Failure Service, Golden Jubilee National Hospital, Glasgow, G81 4DY, United Kingdom. Email E-mail Address: [email protected] https://orcid.org/0000-0003-2531-6071 Department of Transplantation and Mechanical Circulatory Support, Scottish National Advanced Heart Failure Service, Golden Jubilee National Hospital, Glasgow, United Kingdom. Originally published15 May 2023https://doi.org/10.1161/CIRCULATIONAHA.122.063616Circulation. 2023;147:1489–1491FootnotesThe opinions expressed in this article are not necessarily those of the editors or of the American Heart Association.For Sources of Funding and Disclosures, see page 1491.Circulation is available at www.ahajournals.org/journal/circCorrespondence to: Jonathan R. Dalzell, MBChB, MD, Department of Transplantation and Mechanical Circulatory Support, Scottish National Advanced Heart Failure Service, Golden Jubilee National Hospital, Glasgow, G81 4DY, United Kingdom. Email jonathan.dalzell@gjnh.scot.nhs.ukReferences1. Thiele H, Zeymer U, Neumann FJ, Ferenc M, Olbrich HG, Hausleiter J, Richardt G, Hennersdorf M, Empen K, Fuernau G, et al; IABP-SHOCK II Trial Investigators. Intraaortic balloon support for myocardial infarction with cardiogenic shock.N Engl J Med. 2012; 367:1287–1296. doi: 10.1056/NEJMoa1208410CrossrefMedlineGoogle Scholar2. Schrage B, Ibrahim K, Loehn T, Werner N, Sinning J-M, Pappalardo F, Pieri M, Skurk C, Lauten A, Landmesser U, et al. Impella support for acute myocardial infarction complicated by cardiogenic shock.Circulation. 2019; 139:1249–1258. doi: 10.1161/CIRCULATIONAHA.118.036614LinkGoogle Scholar3. Ostadal P, Rokyta R, Karasek J, Kruger A, Vondrakova D, Janotka M, Naar J, Smalcova J, Hubatova M, Hromadka M, et al; ECMO-CS Investigators. Extra-corporeal membrane oxygenation in the therapy of cardiogenic shock: results of the ECMO-CS randomised clinical trial.Circulation. 2023; 147:454–464. doi: 10.1161/CIRCULATIONAHA.122.062949LinkGoogle Scholar4. Akodad M, Delmas C, Bonello L, Duflos C, Roubille F. Intra-aortic balloon pump: is the technique really outdated?ESC Heart Fail. 2020; 7:1025–1030. doi: 10.1002/ehf2.12721CrossrefMedlineGoogle Scholar5. Dhruva SS, Ross JS, Mortazavi BJ, Hurley NC, Krumholz HM, Curtis JP, Berkowitz AP, Masoudi FA, Messenger JC, Parzynski CS, et al. Use of mechanical circulatory support devices among patients with acute myocardial infarction complicated by cardiogenic shock.JAMA Netw Open. 2021; 4:e2037748. doi: 10.1001/jamanetworkopen.2020.37748CrossrefMedlineGoogle Scholar eLetters(0) eLetters should relate to an article recently published in the journal and are not a forum for providing unpublished data. Comments are reviewed for appropriate use of tone and language. Comments are not peer-reviewed. Acceptable comments are posted to the journal website only. Comments are not published in an issue and are not indexed in PubMed. Comments should be no longer than 500 words and will only be posted online. References are limited to 10. Authors of the article cited in the comment will be invited to reply, as appropriate. Comments and feedback on AHA/ASA Scientific Statements and Guidelines should be directed to the AHA/ASA Manuscript Oversight Committee via its Correspondence page. Sign In to Submit a Response to This Article Previous Back to top Next FiguresReferencesRelatedDetailsCited By Pierce J, Applefeld W, Senman B, Loriaux D, Lawler P and Katz J (2024) Design and Execution of Clinical Trials in the Cardiac Intensive Care Unit, Critical Care Clinics, 10.1016/j.ccc.2023.09.003, 40:1, (193-209), Online publication date: 1-Jan-2024. May 16, 2023Vol 147, Issue 20 Advertisement Article Information Metrics © 2023 American Heart Association, Inc.https://doi.org/10.1161/CIRCULATIONAHA.122.063616PMID: 37186686 Originally publishedMay 15, 2023 Keywordscardiogenic shockextracorporeal membrane oxygenationheart-assist deviceintra-aortic balloon pumpPDF download Advertisement Subjects Cardiopulmonary Resuscitation and Emergency Cardiac Care Heart Failure