Synthesis of 3-aminoindenes and cis-1-aminoindanes by Zn(OTf)2-catalyzed cyclization of o-alkynylbenzaldehydes with tertiary alkyl primary amines

A one-pot two-step cyclocarboamination of o -alkynylbenzaldehydes with tertiary alkyl primary amines was realized to afford a range of 3-aminoindenes and cis -1-amino-2-arylindanes with excellent chemo- and diastereo-selectivity.