Clinical Translation of Antibody Positron Emission Tomography for Cancer Imaging

Summary Hepatocellular carcinoma (HCC) lacks precise and noninvasive diagnostic tools. To address this, a new positron emission tomography (PET) radiotracer, [68Ga]Ga-XH-06, was developed. It uses an antibody fragment to target glypican-3 (GPC3), a highly specific biomarker, successfully visualizing GPC3 expressions in patients with HCC, potentially meeting an important unmet need. See related article by Lin et al., p. XX