Treatment for Abdominal Wall Endometriosis: Ultrasound-guided Percutaneous Injection of Lauromacrogol Sclerotherapy

Abdominal wall endometriosis (AWE) is a rare form of endometriosis. Surgical excision is commonly used to treat AWE, but extensive surgical excision may result in other complications. Some scholars have also used high-intensity focused ultrasound, cryoablation, and thermal ablation to treat AWE [ 1 Zhu X Chen L Deng X Xiao S Ye M Xue M. A comparison between high-intensity focused ultrasound and surgical treatment for the management of abdominal wall endometriosis. BJOG. 2017; 124: 53-58 Crossref PubMed Scopus (32) Google Scholar ]. Sclerotherapy is an effective alternative for pelvic endometriosis [ 2 Kim GH Kim PH Shin JH Nam IC Chu HH Ko HK Ultrasound-guided sclerotherapy for the treatment of ovarian endometrioma: an updated systematic review and meta-analysis. Eur Radiol. 2022; 32: 1726-1737 Crossref PubMed Scopus (4) Google Scholar ]. Bozkurt et al. [ 3 Bozkurt M Çil AS Bozkurt DK. Intramuscular abdominal wall endometriosis treated by ultrasound-guided ethanol injection. Clin Med Res. 2014; 12: 160-165 Crossref PubMed Scopus (26) Google Scholar ] treated AWE with sclerotherapy by alcohol injection. Lauromacrogol is a new type of sclerosing agent that targets the endothelial cell and causes protein denaturation and cell death [ 4 Doganci S Yildirim V Erol G et al. Polidocanol (lauromacrogol 400) has anti-angiogenic effects in vitro and in vivo. Eur Rev Med Pharmacol Sci. 2016; 20: 1384-1389 PubMed Google Scholar ].