肿瘤抑制因子
糖蛋白130
肿瘤坏死因子α
医学
受体
内科学
细胞因子
内分泌学
白细胞介素6
作者
Georgios Kokkotis,Eirini Filidou,Gesthimani Tarapatzi,Michail Spathakis,Leonidas Kandilogiannakis,Nikolas Dovrolis,Konstantinos Arvanitidis,Ioannis Drygiannakis,Vassilis Valatas,Stergios Vradelis,Vangelis G. Manolopoulos,Vasilis Paspaliaris,George Kolios,Giorgos Bamias
摘要
Oncostatin-M (OSM) is associated with antitumor necrosis factor (anti-TNF)-α resistance in inflammatory bowel disease (IBD) and fibrosis in inflammatory diseases. We studied the expression of OSM and its receptors (OSMR, gp130) on intestinal subepithelial myofibroblasts (SEMFs) and the effect of OSM stimulation on SEMFs.
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