An Overview of the Mechanisms of Marine Fungi-Derived Anti-Inflammatory and Anti-Tumor Agents and their Novel Role in Drug Targeting

海洋真菌 人类健康 药理学 生物 计算生物学 药品 医学 生态学 环境卫生
作者
Syed Shams ul Hassan,Ishaq Muhammad,Weidong Zhang,Hui‐Zi Jin
出处
期刊:Current Pharmaceutical Design [Bentham Science]
卷期号:27 (22): 2605-2614 被引量:24
标识
DOI:10.2174/1381612826666200728142244
摘要

Marine fungi with their successful pharmacological effects were considered to be the treasure of ocean medicines concerning the striking ability of their secondary metabolites. Literature over literature has been published on fungi derived bioactive molecules to probe its therapeutic potential. Marine fungi have an implicit to cede future medicines against life-threatening diseases, such as cancer and several emerging inflammations. The biological actions of many marine fungi-derived secondary metabolites are still unlocked, for an assorted number of bioactive compounds by which they interact with human diseases are discussed here with comprehensive diagrams. This knowledge is one of the main tracks to be established specifically for the successful transformation of bioactive compounds to medicines. Marine fungi produce a diverse range of biochemical substances with precious carbon scaffolds, which are the main component interplaying with human diseases at distinctive spots. Specific diseases having a flair to fight at distinctive targets within the body can lead to a new trend of raising the chances of developing targeted drugs.
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