Endoscopic Endonasal Nasopharyngectomy and Its Use in Rt3 and Rt4 Recurrent Nasopharyngeal Carcinoma

Background: Endoscopic endonasal nasopharyngectomy (EEN) has been extensively used for rT1 and rT2 recurrent nasopharyngeal carcinoma (rNPC); however, limited literature exists about its use in recurrent T3 (rT3) and T4 (rT4) rNPC. We have performed a systematic review of the literature and reported preliminary data regarding the efficacy and safety of its use in rT3 and rT4 rNPC.