Study of the Relations between Intracranial Pressure and Skull Defect Syndrome under the State of Skull Defect

Objective To study the relations between intracranial pressure and skull defect syndrome under the pathologic state of skull defect. Method The intracranial pressures of 147 patients with skull defect were measured through lumbar puncture before and after cranioplasty and the relations between intracranial pressure and skull defect syndrome were analyzed. Result 9 patient with skull defect area ≤25 cm 2, intracranial pressure 95～165 mm H 2O had no skull defect syndrome, 7 of 26 patients with skull defect area 25～35 cm 2 intracranial pressure 40～150 mm H 2O had skull defect syndrome, 112 of 113 patients with skull defect area ≥35 cm 2, intracranial pressure 0～70 mm H 2O had skull defect syndrome and 117 of 125 patients with intracranial pressure ≤80 mm H 2O had skull defect syndrome. The skull defect syndrome disappeared after cranioplasty and after intracranial pressure recovered to normal. Conclusion Under skull defect state the intracranial pressure has relations with skull defect area. The decrease of intracranial pressure may be an important cause leading to skull defect syndrome.