菌群(微生物学)
肠道菌群
炎症性肠病
发病机制
溃疡性结肠炎
免疫学
疾病
炎症性肠病
病因学
克罗恩病
生物
医学
细菌
病理
遗传学
出处
期刊:PubMed
日期:2013-08-01
卷期号:44 (4): 247-52
被引量:1
摘要
Inflammatory bowel diseases (IBD), including ulcerative colitis (UC) and Crohn's disease (CD), are chronic inflammatory disorders of the intestine. Both the etiology and the pathogenesis of IBD remain unclear. In recent years, the role of gut flora in IBD has become one of the most concerned issues. International metagenomic projects targeting the gut microbiota greatly promote the exploration of the role of gut flora in IBD. What are the characteristics of gut flora in IBD? How does it interact with host susceptibility? This review will discuss the enteric dysbacteriosis in IBD and show the interaction between gut flora, especially the dominant gut flora, and host susceptibility in IBD.
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