Review: In trigeminal neuralgia, carbamazepine, botulinum toxin type A, or lidocaine improve response rate vs placebo

ACP Journal Club16 October 2018Review: In trigeminal neuralgia, carbamazepine, botulinum toxin type A, or lidocaine improve response rate vs placeboDaniel I. Steinberg, MDDaniel I. Steinberg, MDIcahn School of Medicine at Mount Sinai, New York City, New York, USA (D.I.S.)Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/ACPJC-2018-169-8-043 SectionsAboutFull TextPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail Source CitationYang F, Lin Q, Dong L, Gao X, Zhang S. Efficacy of 8 different drug treatments for patients with trigeminal neuralgia: a network meta-analysis. Clin J Pain. 2018;34:685-90. https://pubmed.ncbi.nlm.nih.gov/29200017Clinical Impact RatingsGIM/FP/GP: Geriatrics: Neurology: References1 Gronseth G, Cruccu G, Alksne J, et al. Practice parameter: the diagnostic evaluation and treatment of trigeminal neuralgia (an evidence-based review): report of the Quality Standards Subcommittee of the American Academy of Neurology and the European Federation of Neurological Societies. Neurology. 2008;71:1183-90. [PMID: 18716236] Google Scholar2 Wiffen PJ, Derry S, Moore RA, Kalso EA. Carbamazepine for chronic neuropathic pain and fibromyalgia in adults. Cochrane Database Syst Rev. 2014;4:CD005451. [PMID: 24719027] Google Scholar3 Niki Y, Kanai A, Hoshi K, Okamoto H. Immediate analgesic effect of 8% lidocaine applied to the oral mucosa in patients with trigeminal neuralgia. Pain Med. 2014;15:826-31. [PMID: 24506194] Google Scholar4 Wu CJ, Lian YJ, Zheng YK, et al. Botulinum toxin type A for the treatment of trigeminal neuralgia: results from a randomized, double-blind, placebo-controlled trial. Cephalalgia. 2012;32:443-50. [PMID: 22492424] Google Scholar5 Zhang H, Lian Y, Ma Y, et al. Two doses of botulinum toxin type A for the treatment of trigeminal neuralgia: observation of therapeutic effect from a randomized, double-blind, placebo-controlled trial. J Headache Pain. 2014;15:65. [PMID: 25263254] Google Scholar Author, Article, and Disclosure InformationAffiliations: Icahn School of Medicine at Mount Sinai, New York City, New York, USA (D.I.S.)This article was published at Annals.org on 2 October 2018. PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics 16 October 2018Volume 169, Issue 8Page: JC43KeywordsBotulinum toxinDrugsNetwork analysisNeurologyNeuropathic painNumber needed to harmOdds ratioPatientsSystematic reviewsTreatment guidelines ePublished: 16 October 2018 Issue Published: 16 October 2018 Copyright & PermissionsCopyright © 2018 by American College of Physicians. All Rights Reserved.PDF downloadLoading ...