Visible‐Light Photoredox Catalyzed Regioselective 1,4‐Hydroalkylation of 1,3‐Enyne

Abstract Described herein is a visible‐light photoredox‐catalyzed regioselective 1,4‐hydroalkylation of 1,3‐enynes. Various of di‐ and tri‐substituent allenes were really accessible under the present reaction conditions. The visible‐light photoredox activation of the carbon nucleophile to generate its radical species, allowing the addition with un‐activated enynes. The synthetic utility for the present protocol was demonstrated by a large‐scale reaction, as well as the derivatization of the allene product.