摘要
Background Cyberchondria is often associated with psychological distress, straining doctor-patient relationships, and financial burdens. Over the past few decades, increasing research has explored its associations with quality of life (QoL). However, existing reviews have not comprehensively synthesized or narratively analyzed these connections. Objective This study aims to consolidate current research, identify key trends, and examine how cyberchondria affects QoL, while providing insights for future research directions. Methods The literature search was conducted on 4 databases PsycINFO, PubMed, CINAHL, and Web of Science. The review was restricted to peer-reviewed journals published in English from inception to October 9, 2025. The inclusion criteria were as follows (1) original studies examining health-related factors associated with cyberchondria, (2) participants of any demographic, and (3) English-language full texts. Studies were excluded if they assessed health anxiety as a representation of cyberchondria. The Newcastle-Ottawa Scale for cross-sectional studies was used to assess the risk of bias in the included studies. Narrative analysis was used for data synthesis. This review was reported in accordance with the PRISMA-ScR (Preferred Reporting Items for Systematic Reviews and Meta-Analyses extension for Scoping Reviews) checklist. Results A total of 9483 records were identified from 4 databases, with 87 studies meeting the inclusion criteria for this review. All of the included studies used a cross-sectional design. Most of the included studies were rated as moderate risk (54.4%) to low risk (36.7%). Correlations were found between cyberchondria and QoL domains, including physical health (eg, pain and discomfort, sleep quality), psychological health (eg, anxiety, fear, negative feelings or emotions, anxiety sensitivity, intolerance of uncertainty, obsessive-compulsive symptoms, and depression), level of independence (eg, usual or daily activities, and mobility), social relationship (eg, personal relationship, communication, and social support), environment (eg, eHealth literacy and financial satisfaction), and behavior (eg, addictive behavior). Conclusions This scoping review synthesizes key risk factors and challenges influencing the QoL in individuals with cyberchondria. The findings emphasize the need for clinicians to adopt a holistic approach to assess and manage cyberchondria, addressing its multifaceted impact on QoL.