Progress of bone mechanostat with osteocyte involved

Osteocyte is the chief sense cell of mechanical loads, It reacts to different mechanical stimuli and participates in bone remodeling. Furthermore, osteocyte can regulate the formation and resorption of bone via affecting osteoclast and osteoblast, and play an important role in bone mechanostat. This article reviewed the effect of osteocyte on mechanostat and its influence on osteoblast and osteoclast in order to provide some new ideas for the study of osteocyte biomechanics.