Clinical efficacy of entecavir combined with Ganxin mixture on patients at decompensation stage of hepatic cirrhosis

Objective:To investigate the effect of entecavir(ETV) combined with Ganxin mixture on patients at decompensation stage of hepatic cirrhosis.Methods:A total of 80 cases were randomly divided into control group and treatment group with 40 cases per group.The control group received comprehensive therapy and ETV 0.5 mg/d,once a day,while the treatment was treated with ETV 0.5 mg/d,once a day and Gan xin mixture twice a day with for half a year besides the comprehensive therapy.Liver function,quantitative level of HBV DNA and Child-Pugh scale was were assessed before and after treatment.Results:Compared with control group,the liver function was improved,HBV was inhibited and score of Child-Pugh scale was decreased in treatment group(P0.05).Conclusion:Combined therapy of ETV and Ganxin mixture is effective on patients at decompensation stage of hepatic cirrhosis.It can improve liver function,control HBV copy(P0.05)and decrease Child-Pugh score.