卵巢癌
激酶
癌症
癌细胞
生物
癌症研究
细胞生物学
医学
内科学
出处
期刊:Cancer Discovery
[American Association for Cancer Research]
日期:2016-09-07
卷期号:6 (10): OF1-OF1
被引量:1
标识
DOI:10.1158/2159-8290.cd-nb2016-109
摘要
A recent study reveals that the kinase SIK2 helps ovarian cancer cells metastasize and establish themselves in the fat-rich tissues of the abdominal cavity by promoting fatty-acid metabolism and cell proliferation. Mice bearing SIK2-overexpressing human ovarian cancer cells had larger, more abundant metastases than those whose tumors bore an inactive form of the kinase.
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