Streptomycindole, an Indole Alkaloid from a Marine Streptomyces sp. DA22 Associated with South China Sea Sponge Craniella australiensis

Abstract A new indole alkaloid, streptomycindole ( 1 ), and a known related compound, N ‐phenylacetyl‐ L ‐tryptophan ( 2 ), have been isolated from Streptomyces sp . DA22, associated with South China Sea sponge Craniella australiensis. Their structures were established on the basis of a combination of mass spectrometry, 1 H‐ and 13 C‐NMR spectroscopic analyses, and chemical methods.