Foot and mouth disease (FMD) affects cloven-footed animals. It is caused by seven species (types) of Foot and Mouth virus (FMDV) in the genus aphthovirus, family Picornaviridae (). FMDV is a single-stranded RNA virus, with a protein coat consisting of four capsid proteins enumerated as VP1, VP2, VP3, and VP4 (Garland and Donaldson 1990).