生物相容性材料
纳米技术
纳米颗粒
癌症治疗
癌症
医学
材料科学
生物医学工程
内科学
作者
Feng Chen,Emily B. Ehlerding,Weibo Cai
标识
DOI:10.2967/jnumed.114.146019
摘要
Theranostic nanoparticles hold the potential to revolutionize disease management. Over the last decade, there has been growing interest in the engineering of various kinds of theranostic nanoparticles for simultaneous cancer imaging and therapy in small animals. Efficient targeting of theranostic nanoparticles to the tumor site is critical for both diagnosis and therapy. However, difficulties still exist in the engineering of biocompatible theranostic nanoparticles with highly specific in vivo tumor-targeting capabilities. Here, we discuss the current and prospective status of theranostic nanoparticles that actively target tumors, as well as the challenges that still exist.
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