The research on periodic operation of a trickle‐bed reactor (TBR) has generated a growing interest over the past 10 years. So far, most of the reactions studied in the literature were single reactions and limited information is available on the effect of periodic operation on the performance of parallel or consecutive reactions. To provide a better understanding, the influence of periodic operation of a TBR on the conversion and selectivity of a consecutive reaction, the hydrogenation of 2‐ethylanthraquinones over a Pd/Al2O3 catalyst, has been investigated.