微量白蛋白尿
氧化应激
谷胱甘肽过氧化物酶
糖尿病肾病
超氧化物歧化酶
内科学
医学
内分泌学
谷胱甘肽
过氧化氢酶
2型糖尿病
糖尿病
化学
生物化学
酶
作者
Anca Artenie,R Artenie,Didona Ungureanu,Adrian Covic
出处
期刊:PubMed
日期:2005-07-12
卷期号:108 (4): 777-81
被引量:2
摘要
Oxidative stress has an important role in genesis of diabetic complications, especially diabetic nephropathy. The aim of the study was to assess correlations between increase of oxidative stress (OS) and the development of microalbuminuria (MA) in type 1 diabetic patients. We determined the oxidative status by measuring the level of superoxide dismutase (SOD-Minanui method), catalase (CAT-Aebi method), glutathione peroxidase (GPx-Fukuzawa method) and glutathione (GSH-Ellman method) in 87 type 1 diabetic patients (44 with normal urinary protein excretion-group A and 43 with MA-group B) and 38 nondiabetic matched controls, before and 24 hours after a test effort. The results of the study point out that a decreased in activity of SOD or in levels of GSH is associated with an increased MA in type 1 diabetic patients.
科研通智能强力驱动
Strongly Powered by AbleSci AI