生物
蛋白酶
寄主(生物学)
盘鲍
贻贝
鲍鱼
互补DNA
牡蛎
基因家族
软体动物
防御机制
动物
牡蛎
生态学
基因
遗传学
酶
渔业
基因表达
生物化学
作者
Jian Lü,Sheng Liu,Ziyan Ruan,Jing Ye,Qianjiang Wu,Sufang Wang,Lin Zhang,Qinggang Xue
出处
期刊:Diseases of Aquatic Organisms
[Inter-Research Science Center]
日期:2021-06-17
卷期号:145: 89-100
被引量:3
摘要
Protease inhibitors are proteins or small polypeptides functioning in numerous biological processes in all organisms. The I84 family of protease inhibitors in the MEROPS database represents a novel protease inhibitor family that has been reported in 2 bivalves, Crassostrea virginica and Sinonovacula constricta , and is believed to play a role in host defense. In the present study, 7 new members of Family I84 were identified in 2 bivalves, Meretrix meretrix and Mytilus galloprovincialis , and 1 gastropod, Haliotis discus hannai , at the mRNA level via cDNA cloning. The expression patterns of the newly identified genes varied in response to salinity stresses and pathogen-associated molecular pattern stimulations, suggesting their involvement in the host defense of related species. Additionally, analyses of sequence data in public databases did not reveal any Family I84 protease inhibitor molecules in non-molluscan animals. The results indicated that Family I84 protease inhibitors are likely mollusk specific, constituting a unique host defense mechanism in molluscan species.
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