Designing of chalcone functionalized 1,2,3-triazole allied bis-organosilanes as potent antioxidants and optical sensor for recognition of Sn2+ and Hg2+ ions

This article presents the design, synthesis and characterization of a series of new acetylenic bis-chalcones (5a-5c) and chalcone functionalized 1,2,3-triazole allied bis-organosilanes (6a-6c) using aldol condensation followed by the Cu(I) catalyzed click strategy. The absorption studies of the designed compounds 5a and 6a were examined towards various metal ions that exhibit their high selectivity and sensitivity towards the recognition of Sn2+ and Hg2+ ions. The sensors show reversible nature upon the addition of disodium salt of ethylenediaminetetraacetic acid. Furthermore, the obtained detection limit with sensors 5a and 6a by plotting calibration curve was 0.34 µM and 0.64 µM for Sn2+ ion and 0.31 µM and 0.15 µM for Hg2+ ion respectively. The association constant value calculated for chemosensors 5a and 6a using the Benesi and Hildebrand plot method was 0.69 × 105 M−1 and 0.18 × 105 M−1 towards Sn2+ ion and 0.67 × 106 M−1 and 0.54 × 106 M−1 towards Hg2+ ion respectively. Moreover, the synthesized compounds 5a and 6a were investigated for their biological application by evaluating their cytotoxicity and antioxidant activity.