伤口愈合
生物医学工程
成纤维细胞
药物输送
再生(生物学)
活性氧
疤痕
药品
材料科学
真皮成纤维细胞
靶向给药
药理学
组织工程
自愈水凝胶
纳米技术
脚手架
炎症
氧化损伤
作者
Guoqing Zhang,Miaomiao Wei,Zihan Zhang,Shixuan Chen,Wenbing Wan
出处
期刊:ACS Nano
[American Chemical Society]
日期:2026-03-26
卷期号:20 (13): 10707-10723
标识
DOI:10.1021/acsnano.6c01964
摘要
-infected wound models confirmed the patch's efficacy in accelerating wound closure, reducing inflammation, and mitigating scar formation. Histopathological analysis and RNA sequencing highlighted its role in modulating inflammatory and collagen deposition pathways, while promoting balanced tissue regeneration. The microneedle system offers a promising platform for wound healing and scar prevention, combining targeted drug delivery with multifunctional therapeutic effects.
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