Dyes illuminate live human embryogenesis

Assisted reproduction is on the rise globally. Cell morphology is commonly used for embryo selection, but the cell biology of early preimplantation development remains poorly understood. In this issue of Cell, Domingo-Muelas et al. reveal novel features of human embryos with critical implications for preimplantation genetic testing. Assisted reproduction is on the rise globally. Cell morphology is commonly used for embryo selection, but the cell biology of early preimplantation development remains poorly understood. In this issue of Cell, Domingo-Muelas et al. reveal novel features of human embryos with critical implications for preimplantation genetic testing. Human embryo live imaging reveals nuclear DNA shedding during blastocyst expansion and biopsyDomingo-Muelas et al.CellJuly 5, 2023In BriefLive imaging of human embryos unveils differences from mouse development and reveals DNA shedding from trophectoderm cell nuclei associated with mechanical stress from blastocyst expansion and biopsy for preimplantation genetic testing. Full-Text PDF