As a well-known common neurodegenerative disease in aging, Alzheimer’s disease will cause the loss of the ability to talk, cognization and memorize. Amyloid beta is considered to be a major cause of Alzheimer’s disease. It will form many different types and accumulate in human brain and cause Alzheimer’s disease. However, a recent report about the plagiarism of the fundamental paper of this theory makes many people think that our research direction on Alzheimer’s disease is wrong. The author agrees that the plagiarism of the paper is terrible and should be punished, but the author does not think that this will waste everything we have done about amyloid beta. Amyloid beta is still a major reason that causes Alzheimer’s disease and find a way to stop the accumulation of amyloid beta in brain is a feasible way to cure Alzheimer’s disease. Research on the role of amyloid beta in Alzheimer’s disease, whether it is a major cause is the major purpose of the essay. What’s more a new method that aim to reduce amyloid beta in brain to cure and relief Alzheimer’s disease will be introduced in this article. This method aims to stop the signal transduction of amyloid beta to neuron cells, thus, stop amyloid beta from damaging our brain and cause Alzheimer’s disease. The reason this article is written is to confirm the importance of amyloid beta for Alzheimer’s disease. In addition, introduce a new cure method. Since this method is new, conclude the advantages and disadvantages of this method could inspire other researchers, and improve the performance of the drugs developed based on this method to reach the final goal, which is cure the Alzheimer’s disease.